Regulation of T-cell Receptor Gene Expression by Three-Dimensional Locus Conformation and Enhancer Function

The adaptive immune response in vertebrates depends on the expression of antigen-specific receptors in lymphocytes. T-cell receptor (TCR) gene expression is exquisitely regulated during thymocyte development to drive the generation of αβ and γδ T lymphocytes. The TCRα, TCRβ, TCRγ, and TCRδ genes exi...

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Detalles Bibliográficos
Autores principales: Rodríguez-Caparrós, Alonso, Álvarez-Santiago, Jesús, del Valle-Pastor, María Jesús, Suñé, Carlos, López-Ros, Jennifer, Hernández-Munain, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696796/
https://www.ncbi.nlm.nih.gov/pubmed/33187197
http://dx.doi.org/10.3390/ijms21228478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696796/
https://www.ncbi.nlm.nih.gov/pubmed/33187197
http://dx.doi.org/10.3390/ijms21228478

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