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Alendronate/cRGD-Decorated Ultrafine Hyaluronate Dot Targeting Bone Metastasis

In this study, we report the hyaluronate dot (dHA) with multiligand targeting ability and a photosensitizing antitumor model drug for treating metastatic bone tumors. Here, the dHA was chemically conjugated with alendronate (ALN, as a specific ligand to bone), cyclic arginine-glycine-aspartic acid (...

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Detalles Bibliográficos
Autores principales: Lee, Eunsol, Park, Jaeduk, Youn, Yu Seok, Oh, Kyung Taek, Kim, Dongin, Lee, Eun Seong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696888/
https://www.ncbi.nlm.nih.gov/pubmed/33187133
http://dx.doi.org/10.3390/biomedicines8110492