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Therapeutic Strategies to Reduce the Toxicity of Misfolded Protein Oligomers

The aberrant aggregation of proteins is implicated in the onset and pathogenesis of a wide range of neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Mounting evidence indicates that misfolded protein oligomers produced as intermediates in the aggregation process are poten...

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Detalles Bibliográficos
Autores principales: Kreiser, Ryan P., Wright, Aidan K., Block, Natalie R., Hollows, Jared E., Nguyen, Lam T., LeForte, Kathleen, Mannini, Benedetta, Vendruscolo, Michele, Limbocker, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696907/
https://www.ncbi.nlm.nih.gov/pubmed/33212787
http://dx.doi.org/10.3390/ijms21228651