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Cinnamides Target Leishmania amazonensis Arginase Selectively

Caffeic acid and related natural compounds were previously described as Leishmania amazonensis arginase (L-ARG) inhibitors, and against the whole parasite in vitro. In this study, we tested cinnamides that were previously synthesized to target human arginase. The compound caffeic acid phenethyl amid...

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Detalles Bibliográficos
Autores principales: da Silva, Edson Roberto, Come, Júlio Abel Alfredo dos Santos Simone, Brogi, Simone, Calderone, Vincenzo, Chemi, Giulia, Campiani, Giuseppe, Oliveira, Trícia Maria Ferrreira de Sousa, Pham, Thanh-Nhat, Pudlo, Marc, Girard, Corine, Maquiaveli, Claudia do Carmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696938/
https://www.ncbi.nlm.nih.gov/pubmed/33198198
http://dx.doi.org/10.3390/molecules25225271