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Effects of Rationally Designed Physico-Chemical Variants of the Peptide PuroA on Biocidal Activity towards Bacterial and Mammalian Cells

Antimicrobial peptides (AMPs) often exhibit wide-spectrum activities and are considered ideal candidates for effectively controlling persistent and multidrug-resistant wound infections. PuroA, a synthetic peptide based on the tryptophan (Trp)-rich domain of the wheat protein puroindoline A, displays...

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Detalles Bibliográficos
Autores principales: Shagaghi, Nadin, Clayton, Andrew H. A., Aguilar, Marie-Isabel, Lee, Tzong-Hsien, Palombo, Enzo A., Bhave, Mrinal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696940/
https://www.ncbi.nlm.nih.gov/pubmed/33207639
http://dx.doi.org/10.3390/ijms21228624