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Cold-Inducible RNA Binding Protein as a Vaccination Platform to Enhance Immunotherapeutic Responses against Hepatocellular Carcinoma

SIMPLE SUMMARY: Current immunotherapies based on blockade of immunosuppressive elements provide limited results in liver cancer patients. Here we tested whether combination of this therapy with a vaccine based on the Cold-Inducible RNA Binding Protein (CIRP) would improve its efficacy. Combination o...

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Detalles Bibliográficos
Autores principales: Silva, Leyre, Egea, Josune, Villanueva, Lorea, Ruiz, Marta, Llopiz, Diana, Repáraz, David, Aparicio, Belén, Lasarte-Cia, Aritz, Lasarte, Juan José, Ruiz de Galarreta, Marina, Lujambio, Amaia, Sangro, Bruno, Sarobe, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696968/
https://www.ncbi.nlm.nih.gov/pubmed/33207844
http://dx.doi.org/10.3390/cancers12113397