Upregulation of Peroxiredoxin-2 in Well-Differentiated Pancreatic Neuroendocrine Tumors and Its Utility as a Biomarker for Predicting the Response to Everolimus

Pancreatic neuroendocrine neoplasms (pNENs) account for 2–3% of pancreatic malignancies. Peroxiredoxins (Prdxs), which are major cellular antioxidants, are involved in multiple oncogenic signaling pathways. We investigated the role of peroxiredoxin-2 in QGP-1 human pNEN cell line and patient-derived...

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Detalles Bibliográficos
Autores principales: Kim, Eui Joo, Kim, Yoon Jae, Lee, Hye In, Jeong, Seok-Hoo, Nam, Hyo Jung, Cho, Jae Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696978/
https://www.ncbi.nlm.nih.gov/pubmed/33182509
http://dx.doi.org/10.3390/antiox9111104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696978/
https://www.ncbi.nlm.nih.gov/pubmed/33182509
http://dx.doi.org/10.3390/antiox9111104

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