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Interplay of Prenatal and Postnatal Risk Factors in the Behavioral and Histological Features of a “Two-Hit” Non-Genetic Mouse Model of Schizophrenia

Schizophrenia is a multifactorial developmental neuropsychiatric disorder. This study examined the interplay of maternal infection and postweaning social isolation, which are prenatal and postnatal risk factors, respectively. Pregnant mice received poly I:C or saline injection on gestation day 9 and...

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Detalles Bibliográficos
Autores principales: Chang, Yi-Chun, Li, Wai-Yu, Lee, Lukas Jyuhn-Hsiarn, Lee, Li-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697169/
https://www.ncbi.nlm.nih.gov/pubmed/33198225
http://dx.doi.org/10.3390/ijms21228518