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Combination Antitumor Effect of Sorafenib via Calcium-Dependent Deactivation of Focal Adhesion Kinase Targeting Colorectal Cancer Cells

Sorafenib has been recently used for the treatment of patients with advanced colorectal cancer (CRC) and is recognized for its therapeutic value. However, the continuous use of sorafenib may cause resistance in the treatment of cancer patients. In this study, we investigated whether sorafenib exerts...

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Detalles Bibliográficos
Autores principales: Jeong, Keun-Yeong, Park, Minhee, Sim, Jae-Jun, Kim, Hwan Mook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697278/
https://www.ncbi.nlm.nih.gov/pubmed/33202899
http://dx.doi.org/10.3390/molecules25225299