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Design and Engineering of Deimmunized Vaccinia Viral Vectors

Vaccinia viral (VV) vectors are increasingly used in oncolytic virus therapy and vaccine development for cancer and infectious diseases. However, their effectiveness is hindered by the strong anti-viral immune response induced by the viral vector. In this review, we discuss the strategies to deimmun...

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Detalles Bibliográficos
Autores principales: Song, Kevin, Viskovska, Mariya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697509/
https://www.ncbi.nlm.nih.gov/pubmed/33187060
http://dx.doi.org/10.3390/biomedicines8110491