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Deciphering Fatty Acid Synthase Inhibition-Triggered Metabolic Flexibility in Prostate Cancer Cells through Untargeted Metabolomics

Fatty acid synthase (FAS) is a key enzyme involved in de novo lipogenesis that produces lipids that are necessary for cell growth and signal transduction, and it is known to be overexpressed, especially in cancer cells. Although lipid metabolism alteration is an important metabolic phenotype in canc...

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Detalles Bibliográficos
Autores principales: Oh, Ju Eun, Jung, Byung Hwa, Park, Jinyoung, Kang, Soosung, Lee, Hyunbeom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697567/
https://www.ncbi.nlm.nih.gov/pubmed/33182594
http://dx.doi.org/10.3390/cells9112447