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Blood–Brain Barrier Modulation to Improve Glioma Drug Delivery
The blood–brain barrier (BBB) is formed by brain microvascular endothelial cells that are sealed by tight junctions, making it a significant obstacle for most brain therapeutics. The poor BBB penetration of newly developed therapeutics has therefore played a major role in limiting their clinical suc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697580/ https://www.ncbi.nlm.nih.gov/pubmed/33198244 http://dx.doi.org/10.3390/pharmaceutics12111085 |