Gynecological Cancers Caused by Deficient Mismatch Repair and Microsatellite Instability

SIMPLE SUMMARY: Microsatellite instability (MSI) has been detected in multiple types of gynecologic cancers. MSI is linked to mutations in mismatch repair (MMR) genes that cause mismatch repair deficit (dMMR) in human cells. Discovery of new therapeutic approaches are needed especially for treatment...

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Detalles Bibliográficos
Autores principales: Deshpande, Madhura, Romanski, Phillip A., Rosenwaks, Zev, Gerhardt, Jeannine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697596/
https://www.ncbi.nlm.nih.gov/pubmed/33182707
http://dx.doi.org/10.3390/cancers12113319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697596/
https://www.ncbi.nlm.nih.gov/pubmed/33182707
http://dx.doi.org/10.3390/cancers12113319

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