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The 40bp Indel Polymorphism rs150550023 in the MDM2 Promoter is Associated with Intriguing Shifts in Gene Expression in the p53-MDM2 Regulatory Hub

SIMPLE SUMMARY: Many naturally occurring variants in the human DNA sequence have an influence on cancer risk, and most of them are located outside the parts of the genome that code for proteins. Presumably, they have an effect on the amount of messenger RNA and protein that is made from genes in the...

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Detalles Bibliográficos
Autores principales: Miedl, Heidi, Dietrich, Bianca, Kaserer, Klaus, Schreiber, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697608/
https://www.ncbi.nlm.nih.gov/pubmed/33202864
http://dx.doi.org/10.3390/cancers12113363