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The Importance of Hypoxia-Inducible Factors (HIF-1 and HIF-2) for the Pathophysiology of Inflammatory Bowel Disease

(1) Background: Hypoxia is a common feature of inflammation when hypoxia inducible factors (HIFs) adapt cells to conditions of low oxygen tension and inflammation. We studied the role of HIF-1 and HIF-2 in cells of the myeloid lineage in a mouse model of acute colitis. (2) Methods: Mice with and wit...

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Detalles Bibliográficos
Autores principales: Kerber, Evelyn L., Padberg, Claudia, Koll, Nora, Schuetzhold, Vera, Fandrey, Joachim, Winning, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697655/
https://www.ncbi.nlm.nih.gov/pubmed/33202783
http://dx.doi.org/10.3390/ijms21228551