Design, Synthesis and Biological Evaluation of (2′,5′ and 3′5′-Linked) cGAMP Analogs that Activate Stimulator of Interferon Genes (STING)

Stimulator of interferon genes (STING) is an endoplasmic reticulum adaptor transmembrane protein that plays a pivotal role in innate immune system. STING agonists, such as endogenous cyclic dinucleotide (CDN) cyclic GMP-AMP (cGAMP), have been used in diverse clinical research for immunogenic tumor c...

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Detalles Bibliográficos
Autores principales: Xie, Xin, Liu, Junyi, Wang, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697705/
https://www.ncbi.nlm.nih.gov/pubmed/33198423
http://dx.doi.org/10.3390/molecules25225285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697705/
https://www.ncbi.nlm.nih.gov/pubmed/33198423
http://dx.doi.org/10.3390/molecules25225285

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