MicroRNA-23a-3p Down-Regulation in Active Pulmonary Tuberculosis Patients with High Bacterial Burden Inhibits Mononuclear Cell Function and Phagocytosis through TLR4/TNF-α/TGF-β1/IL-10 Signaling via Targeting IRF1/SP1

The aim of this study is to explore the role of microRNAs (miR)-21/23a/146a/150/155 targeting the toll-like receptor pathway in active tuberculosis (TB) disease and latent TB infection (LTBI). Gene expression levels of the five miRs and predicted target genes were assessed in peripheral blood mononu...

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Detalles Bibliográficos
Autores principales: Chen, Yung-Che, Lee, Chiu Ping, Hsiao, Chang-Chun, Hsu, Po-Yuan, Wang, Ting-Ya, Wu, Chao-Chien, Chao, Tung-Ying, Leung, Sum-Yee, Chang, Yu-Ping, Lin, Meng-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697976/
https://www.ncbi.nlm.nih.gov/pubmed/33202583
http://dx.doi.org/10.3390/ijms21228587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697976/
https://www.ncbi.nlm.nih.gov/pubmed/33202583
http://dx.doi.org/10.3390/ijms21228587

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