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MicroRNA-23a-3p Down-Regulation in Active Pulmonary Tuberculosis Patients with High Bacterial Burden Inhibits Mononuclear Cell Function and Phagocytosis through TLR4/TNF-α/TGF-β1/IL-10 Signaling via Targeting IRF1/SP1
The aim of this study is to explore the role of microRNAs (miR)-21/23a/146a/150/155 targeting the toll-like receptor pathway in active tuberculosis (TB) disease and latent TB infection (LTBI). Gene expression levels of the five miRs and predicted target genes were assessed in peripheral blood mononu...
Autores principales: | Chen, Yung-Che, Lee, Chiu Ping, Hsiao, Chang-Chun, Hsu, Po-Yuan, Wang, Ting-Ya, Wu, Chao-Chien, Chao, Tung-Ying, Leung, Sum-Yee, Chang, Yu-Ping, Lin, Meng-Chih |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697976/ https://www.ncbi.nlm.nih.gov/pubmed/33202583 http://dx.doi.org/10.3390/ijms21228587 |
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