Small-Dose Sunitinib Modulates p53, Bcl-2, STAT3, and ERK1/2 Pathways and Protects against Adenine-Induced Nephrotoxicity

The therapeutic use of numerous pharmacological agents may be limited due to their nephrotoxicity and associated kidney injury. The aim of our study is to test the hypothesis that the blockade of tyrosine kinase-linked receptors signaling protects against chemically induced nephrotoxicity. To test o...

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Detalles Bibliográficos
Autores principales: Saleh, Mohamed A., Awad, Ahmed M., Ibrahim, Tarek M., Abu-Elsaad, Nashwa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698013/
https://www.ncbi.nlm.nih.gov/pubmed/33212804
http://dx.doi.org/10.3390/ph13110397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698013/
https://www.ncbi.nlm.nih.gov/pubmed/33212804
http://dx.doi.org/10.3390/ph13110397

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