Platinum-Based Drugs Cause Mitochondrial Dysfunction in Cultured Dorsal Root Ganglion Neurons

Cisplatin and oxaliplatin are treatment options for a variety of cancer types. While highly efficient in killing cancer cells, both chemotherapeutics cause severe side effects, e.g., peripheral neuropathies. Using a cell viability assay, a mitochondrial stress assay, and live-cell imaging, the effec...

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Detalles Bibliográficos
Autores principales: Leo, Markus, Schmitt, Linda-Isabell, Küsterarent, Patricia, Kutritz, Andrea, Rassaf, Tienush, Kleinschnitz, Christoph, Hendgen-Cotta, Ulrike B., Hagenacker, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698191/
https://www.ncbi.nlm.nih.gov/pubmed/33207782
http://dx.doi.org/10.3390/ijms21228636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698191/
https://www.ncbi.nlm.nih.gov/pubmed/33207782
http://dx.doi.org/10.3390/ijms21228636

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