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Detection of Low-Level Fosfomycin-Resistant Variants by Decreasing Glucose-6-Phosphate Concentration in Fosfomycin Susceptibility Determination

Mutations that confer low-level fosfomycin resistance (LLFR) but not clinical resistance in Escherichia coli are increasingly reported. LLFR strains can become clinically resistant under urinary tract physiological conditions or may act as gateways for highly resistant subpopulations by the selectio...

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Detalles Bibliográficos
Autores principales: Martín-Gutiérrez, Guillermo, Docobo-Pérez, Fernando, Rodríguez-Martínez, Jose Manuel, Pascual, Alvaro, Blázquez, Jesús, Rodriguez-Beltrán, Jeronimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698254/
https://www.ncbi.nlm.nih.gov/pubmed/33198311
http://dx.doi.org/10.3390/antibiotics9110802