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Evolutionary Selection of the Nuclear Localization Signal in the Viral Nucleoprotein Leads to Host Adaptation of the Genus Orthobornavirus

Adaptation of the viral life cycle to host cells is necessary for efficient viral infection and replication. This evolutionary process has contributed to the mechanism for determining the host range of viruses. Orthobornaviruses, members of the family Bornaviridae, are non-segmented, negative-strand...

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Detalles Bibliográficos
Autores principales: Komorizono, Ryo, Sassa, Yukiko, Horie, Masayuki, Makino, Akiko, Tomonaga, Keizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698282/
https://www.ncbi.nlm.nih.gov/pubmed/33187187
http://dx.doi.org/10.3390/v12111291