Synthesis of Conformationally Constrained d-Glu-meso-DAP Analogs as Innate Immune Agonists

The dipeptide d-Glu-meso-DAP (iE-DAP) is the minimal structural fragment capable of activating the innate immune receptor nucleotide-binding oligomerization domain protein (NOD1). The meso-diaminopimelic acid (meso-DAP) moiety is known to be very stringent in terms of the allowed structural modifica...

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Detalles Bibliográficos
Autores principales: Guzelj, Samo, Jakopin, Žiga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698283/
https://www.ncbi.nlm.nih.gov/pubmed/33182604
http://dx.doi.org/10.3390/molecules25225228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698283/
https://www.ncbi.nlm.nih.gov/pubmed/33182604
http://dx.doi.org/10.3390/molecules25225228

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