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DNase I Induces Other Endonucleases in Kidney Tubular Epithelial Cells by Its DNA-Degrading Activity

Endonuclease-mediated DNA fragmentation is both an immediate cause and a result of apoptosis and of all other types of irreversible cell death after injury. It is produced by nine enzymes including DNase I, DNase 2, their homologs, caspase-activated DNase (CAD) and endonuclease G (EndoG). The endonu...

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Detalles Bibliográficos
Autores principales: Fahmi, Tariq, Wang, Xiaoying, Zhdanov, Dmitry D., Islam, Intisar, Apostolov, Eugene O., Savenka, Alena V., Basnakian, Alexei G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698339/
https://www.ncbi.nlm.nih.gov/pubmed/33212932
http://dx.doi.org/10.3390/ijms21228665