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Marek’s Disease Virus Cluster 3 miRNAs Restrict Virus’ Early Cytolytic Replication and Pathogenesis

Herpesvirus-encoded microRNAs (miRNAs) have been discovered in infected cells; however, lack of a suitable animal model has hampered functional analyses of viral miRNAs in vivo. Marek’s disease virus (MDV) (Gallid alphaherpesvirus 2, GaHV-2) genome contains 14 miRNA precursors, which encode 26 matur...

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Detalles Bibliográficos
Autores principales: Liao, Yifei, Zhuang, Guoqing, Sun, Aijun, Khan, Owais A., Lupiani, Blanca, Reddy, Sanjay M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698348/
https://www.ncbi.nlm.nih.gov/pubmed/33212952
http://dx.doi.org/10.3390/v12111317