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Upregulation of iNOS Protects Cyclic Mechanical Stretch-Induced Cell Death in Rat Aorta Smooth Muscle Cells

Aortic dissection and aneurysm are associated with abnormal hemodynamic loads originating from hypertension. Our previous study demonstrated that cyclic mechanical stretch (CMS, mimicked hypertension) caused the death of rat aortic smooth muscle cells (RASMCs) in a mitogen activated-protein kinases...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Nakahira, Kiichi, Kimura, Akihiko, Kyotani, Yoji, Yoshizumi, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698365/
https://www.ncbi.nlm.nih.gov/pubmed/33212839
http://dx.doi.org/10.3390/ijms21228660