In vitro versus in vivo models of kidney fibrosis: Time-course experimental design is crucial to avoid misinterpretations of gene expression data

BACKGROUND: In vitro models are common tools in nephrology research. However, their validity has rarely been scrutinized. MATERIALS AND METHODS: Considering the critical role of transforming growth factor (TGF)-β and hypoxia pathways in kidney fibrosis, kidney-derived cells were exposed to TGF-β and...

Descripción completa

Detalles Bibliográficos
Autores principales: Moein, Shiva, Moradzadeh, Kobra, Javanmard, Shaghayegh Haghjooy, Nasiri, Seyed Mahdi, Gheisari, Yousof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698384/
https://www.ncbi.nlm.nih.gov/pubmed/33273929
http://dx.doi.org/10.4103/jrms.JRMS_906_19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698384/
https://www.ncbi.nlm.nih.gov/pubmed/33273929
http://dx.doi.org/10.4103/jrms.JRMS_906_19

Ejemplares similares