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In vitro versus in vivo models of kidney fibrosis: Time-course experimental design is crucial to avoid misinterpretations of gene expression data
BACKGROUND: In vitro models are common tools in nephrology research. However, their validity has rarely been scrutinized. MATERIALS AND METHODS: Considering the critical role of transforming growth factor (TGF)-β and hypoxia pathways in kidney fibrosis, kidney-derived cells were exposed to TGF-β and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wolters Kluwer - Medknow
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698384/ https://www.ncbi.nlm.nih.gov/pubmed/33273929 http://dx.doi.org/10.4103/jrms.JRMS_906_19 |