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Rheumatoid Arthritis: Applicability of Ready-to-Use Human Cartilaginous Cells for Screening of Compounds with TNF-Alpha Inhibitory Activity

In the context of modern drug discovery, there is an obvious advantage to designing phenotypic bioassays based on human disease-relevant cells that express disease-relevant markers. The specific aim of the study was to develop a convenient and reliable method for screening compounds with Tumor Necro...

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Detalles Bibliográficos
Autores principales: Volova, Larissa T., Pugachev, Evgeniy I., Rossinskaya, Victoria V., Boltovskaya, Violetta V., Dolgushkin, Dmitry A., Ossina, Natalya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698400/
https://www.ncbi.nlm.nih.gov/pubmed/33212930
http://dx.doi.org/10.3390/biom10111563