Polygenetic-Risk Scores Related to Crystallin Metabolism Are Associated with Age-Related Cataract Formation and Interact with Hyperglycemia, Hypertension, Western-Style Diet, and Na Intake

Age-related cataract (ARC) development is associated with loss of crystalline lens transparency related to interactions between genetic and environmental factors. We hypothesized that polygenetic risk scores (PRS) of the selected genetic variants among the ARC-related genes might reveal significant...

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Detalles Bibliográficos
Autores principales: Jee, Donghyun, Kang, Suna, Huang, ShaoKai, Park, Sunmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698476/
https://www.ncbi.nlm.nih.gov/pubmed/33213085
http://dx.doi.org/10.3390/nu12113534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698476/
https://www.ncbi.nlm.nih.gov/pubmed/33213085
http://dx.doi.org/10.3390/nu12113534

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