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Transthyretin Stabilization: An Emerging Strategy for the Treatment of Alzheimer’s Disease?
Transthyretin (TTR), previously named prealbumin is a plasma protein secreted mainly by the liver and choroid plexus (CP) that is a carrier for thyroid hormones (THs) and retinol (vitamin A). The structure of TTR, with four monomers rich in β-chains in a globular tetrameric protein, accounts for the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698513/ https://www.ncbi.nlm.nih.gov/pubmed/33212973 http://dx.doi.org/10.3390/ijms21228672 |