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Pangenome Analysis of Mycobacterium tuberculosis Reveals Core-Drug Targets and Screening of Promising Lead Compounds for Drug Discovery

Tuberculosis, caused by Mycobacterium tuberculosis (M. tuberculosis), is one of the leading causes of human deaths globally according to the WHO TB 2019 report. The continuous rise in multi- and extensive-drug resistance in M. tuberculosis broadens the challenges to control tuberculosis. The availab...

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Detalles Bibliográficos
Autores principales: Dar, Hamza Arshad, Zaheer, Tahreem, Ullah, Nimat, Bakhtiar, Syeda Marriam, Zhang, Tianyu, Yasir, Muhammad, Azhar, Esam I., Ali, Amjad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698547/
https://www.ncbi.nlm.nih.gov/pubmed/33213029
http://dx.doi.org/10.3390/antibiotics9110819