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Variable Selection in Untargeted Metabolomics and the Danger of Sparsity

The goal of metabolomics is to measure as many metabolites as possible in order to capture biomarkers that may indicate disease mechanisms. Variable selection in chemometric methods can be divided into the following two groups: (1) sparse methods that find the minimal set of variables to discriminat...

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Detalles Bibliográficos
Autores principales: Tinnevelt, Gerjen H., Engelke, Udo F.H., Wevers, Ron A., Veenhuis, Stefanie, Willemsen, Michel A., Coene, Karlien L.M., Kulkarni, Purva, Jansen, Jeroen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698561/
https://www.ncbi.nlm.nih.gov/pubmed/33213095
http://dx.doi.org/10.3390/metabo10110470