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Glucose Concentration in Cell Culture Medium Influences the BRCA1-Mediated Regulation of the Lipogenic Action of IGF-I in Breast Cancer Cells

Hyperglycaemia is a common metabolic alteration associated with breast cancer risk and progression. We have previously reported that BRCA1 restrains metabolic activity and proliferative response to IGF-I anabolic actions in breast cancer cells cultured in high glucose. Here, we evaluated the impact...

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Detalles Bibliográficos
Autores principales: Koobotse, Moses O., Schmidt, Dayane, Holly, Jeff M. P., Perks, Claire M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698585/
https://www.ncbi.nlm.nih.gov/pubmed/33212987
http://dx.doi.org/10.3390/ijms21228674