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Design and Synthesis of New Benzo[d]oxazole-Based Derivatives and Their Neuroprotective Effects on β-Amyloid-Induced PC12 Cells

A series of novel synthetic substituted benzo[d]oxazole-based derivatives (5a–5v) exerted neuroprotective effects on β-amyloid (Aβ)-induced PC12 cells as a potential approach for the treatment of Alzheimer’s disease (AD). In vitro studies show that most of the synthesized compounds were potent in re...

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Detalles Bibliográficos
Autores principales: Liu, Zheng, Bian, Ming, Ma, Qian-Qian, Zhang, Zhuo, Du, Huan-Huan, Wei, Cheng-Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698601/
https://www.ncbi.nlm.nih.gov/pubmed/33218007
http://dx.doi.org/10.3390/molecules25225391