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tert-Butyl Hydroperoxide (tBHP)-Induced Lipid Peroxidation and Embryonic Defects Resemble Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in C. elegans

G6PD is required for embryonic development in animals, as severe G6PD deficiency is lethal to mice, zebrafish and nematode. Lipid peroxidation is linked to membrane-associated embryonic defects in Caenorhabditis elegans (C. elegans). However, the direct link between lipid peroxidation and embryonic...

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Detalles Bibliográficos
Autores principales: Yang, Hung-Chi, Yu, Hsiang, Ma, Tian-Hsiang, Tjong, Wen-Ye, Stern, Arnold, Chiu, Daniel Tsun-Yee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698637/
https://www.ncbi.nlm.nih.gov/pubmed/33217954
http://dx.doi.org/10.3390/ijms21228688