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Solubility and Stability Enhanced Oral Formulations for the Anti-Infective Corallopyronin A

Novel-antibiotics are urgently needed to combat an increase in morbidity and mortality due to resistant bacteria. The preclinical candidate corallopyronin A (CorA) is a potent antibiotic against Gram-positive and some Gram-negative pathogens for which a solid oral formulation was needed for further...

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Detalles Bibliográficos
Autores principales: Krome, Anna K., Becker, Tim, Kehraus, Stefan, Schiefer, Andrea, Steinebach, Christian, Aden, Tilman, Frohberger, Stefan J., López Mármol, Álvaro, Kapote, Dnyaneshwar, Jansen, Rolf, Chaverra-Muñoz, Lillibeth, Hübner, Marc P., Pfarr, Kenneth, Hesterkamp, Thomas, Stadler, Marc, Gütschow, Michael, König, Gabriele M., Hoerauf, Achim, Wagner, Karl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698778/
https://www.ncbi.nlm.nih.gov/pubmed/33217948
http://dx.doi.org/10.3390/pharmaceutics12111105