Substrate Specificity and Structural Modeling of Human Carboxypeptidase Z: A Unique Protease with a Frizzled-Like Domain

Metallocarboxypeptidase Z (CPZ) is a secreted enzyme that is distinguished from all other members of the M14 metallocarboxypeptidase family by the presence of an N-terminal cysteine-rich Frizzled-like (Fz) domain that binds Wnt proteins. Here, we present a comprehensive analysis of the enzymatic pro...

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Detalles Bibliográficos
Autores principales: Garcia-Pardo, Javier, Tanco, Sebastian, Garcia-Guerrero, Maria C., Dasgupta, Sayani, Avilés, Francesc Xavier, Lorenzo, Julia, Fricker, Lloyd D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698808/
https://www.ncbi.nlm.nih.gov/pubmed/33217972
http://dx.doi.org/10.3390/ijms21228687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698808/
https://www.ncbi.nlm.nih.gov/pubmed/33217972
http://dx.doi.org/10.3390/ijms21228687

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