Acid Sphingomyelinase Impacts Canonical Transient Receptor Potential Channels 6 (TRPC6) Activity in Primary Neuronal Systems

The acid sphingomyelinase (ASM)/ceramide system exhibits a crucial role in the pathology of major depressive disorder (MDD). ASM hydrolyzes the abundant membrane lipid sphingomyelin to ceramide that regulates the clustering of membrane proteins via microdomain and lipid raft organization. Several co...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeitler, Stefanie, Schumacher, Fabian, Monti, Juliana, Anni, Daniela, Guhathakurta, Debarpan, Kleuser, Burkhard, Friedland, Kristina, Fejtová, Anna, Kornhuber, Johannes, Rhein, Cosima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698877/
https://www.ncbi.nlm.nih.gov/pubmed/33218173
http://dx.doi.org/10.3390/cells9112502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698877/
https://www.ncbi.nlm.nih.gov/pubmed/33218173
http://dx.doi.org/10.3390/cells9112502

Ejemplares similares