Photodynamic Inactivation of Bacteria with Porphyrin Derivatives: Effect of Charge, Lipophilicity, ROS Generation, and Cellular Uptake on Their Biological Activity In Vitro

Resistance of microorganisms to antibiotics has led to research on various therapeutic strategies with different mechanisms of action, including photodynamic inactivation (PDI). In this work, we evaluated a cationic, neutral, and anionic meso-tetraphenylporphyrin derivative’s ability to inactivate t...

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Detalles Bibliográficos
Autores principales: Sułek, Adam, Pucelik, Barbara, Kobielusz, Marcin, Barzowska, Agata, Dąbrowski, Janusz M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698881/
https://www.ncbi.nlm.nih.gov/pubmed/33218103
http://dx.doi.org/10.3390/ijms21228716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698881/
https://www.ncbi.nlm.nih.gov/pubmed/33218103
http://dx.doi.org/10.3390/ijms21228716

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