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Photodynamic Inactivation of Bacteria with Porphyrin Derivatives: Effect of Charge, Lipophilicity, ROS Generation, and Cellular Uptake on Their Biological Activity In Vitro
Resistance of microorganisms to antibiotics has led to research on various therapeutic strategies with different mechanisms of action, including photodynamic inactivation (PDI). In this work, we evaluated a cationic, neutral, and anionic meso-tetraphenylporphyrin derivative’s ability to inactivate t...
Autores principales: | Sułek, Adam, Pucelik, Barbara, Kobielusz, Marcin, Barzowska, Agata, Dąbrowski, Janusz M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698881/ https://www.ncbi.nlm.nih.gov/pubmed/33218103 http://dx.doi.org/10.3390/ijms21228716 |
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