Cargando…

Special Delivery: Potential Mechanisms of Botulinum Neurotoxin Uptake and Trafficking within Motor Nerve Terminals

Botulinum neurotoxins (BoNTs) are highly potent, neuroparalytic protein toxins that block the release of acetylcholine from motor neurons and autonomic synapses. The unparalleled toxicity of BoNTs results from the highly specific and localized cleavage of presynaptic proteins required for nerve tran...

Descripción completa

Detalles Bibliográficos
Autores principales: Winner, Brittany M., Bodt, Skylar M. L., McNutt, Patrick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698961/
https://www.ncbi.nlm.nih.gov/pubmed/33218099
http://dx.doi.org/10.3390/ijms21228715