Sunitinib-Containing Carborane Pharmacophore with the Ability to Inhibit Tyrosine Kinases Receptors FLT3, KIT and PDGFR-β, Exhibits Powerful In Vivo Anti-Glioblastoma Activity

SIMPLE SUMMARY: Glioblastoma is one of the most aggressive central nervous system tumors. Combinations of therapies, such as tyrosine kinase receptor inhibition and boron neutron capture therapy (BNCT), could offer greater patients benefits over single-therapies. The aim of our study was to assess t...

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Detalles Bibliográficos
Autores principales: Alamón, Catalina, Dávila, Belén, García, María Fernanda, Sánchez, Carina, Kovacs, Mariángeles, Trias, Emiliano, Barbeito, Luis, Gabay, Martín, Zeineh, Nidal, Gavish, Moshe, Teixidor, Francesc, Viñas, Clara, Couto, Marcos, Cerecetto, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698965/
https://www.ncbi.nlm.nih.gov/pubmed/33218150
http://dx.doi.org/10.3390/cancers12113423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698965/
https://www.ncbi.nlm.nih.gov/pubmed/33218150
http://dx.doi.org/10.3390/cancers12113423

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