Age-Dependent Decline in Synaptic Mitochondrial Function Is Exacerbated in Vulnerable Brain Regions of Female 3xTg-AD Mice

Synaptic aging has been associated with neuronal circuit dysfunction and cognitive decline. Reduced mitochondrial function may be an early event that compromises synaptic integrity and neurotransmission in vulnerable brain regions during physiological and pathological aging. Thus, we aimed to measur...

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Detalles Bibliográficos
Autores principales: Espino de la Fuente-Muñoz, César, Rosas-Lemus, Mónica, Moreno-Castilla, Perla, Bermúdez-Rattoni, Federico, Uribe-Carvajal, Salvador, Arias, Clorinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699171/
https://www.ncbi.nlm.nih.gov/pubmed/33227902
http://dx.doi.org/10.3390/ijms21228727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699171/
https://www.ncbi.nlm.nih.gov/pubmed/33227902
http://dx.doi.org/10.3390/ijms21228727

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