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Age-Dependent Decline in Synaptic Mitochondrial Function Is Exacerbated in Vulnerable Brain Regions of Female 3xTg-AD Mice
Synaptic aging has been associated with neuronal circuit dysfunction and cognitive decline. Reduced mitochondrial function may be an early event that compromises synaptic integrity and neurotransmission in vulnerable brain regions during physiological and pathological aging. Thus, we aimed to measur...
Autores principales: | Espino de la Fuente-Muñoz, César, Rosas-Lemus, Mónica, Moreno-Castilla, Perla, Bermúdez-Rattoni, Federico, Uribe-Carvajal, Salvador, Arias, Clorinda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699171/ https://www.ncbi.nlm.nih.gov/pubmed/33227902 http://dx.doi.org/10.3390/ijms21228727 |
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