Identification and Validation of Carbonic Anhydrase II as the First Target of the Anti-Inflammatory Drug Actarit

Background and purpose: Identifying the macromolecular targets of drug molecules is a fundamental aspect of drug discovery and pharmacology. Several drugs remain without known targets (orphan) despite large-scale in silico and in vitro target prediction efforts. Ligand-centric chemical-similarity-ba...

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Detalles Bibliográficos
Autores principales: Ghislat, Ghita, Rahman, Taufiq, Ballester, Pedro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699199/
https://www.ncbi.nlm.nih.gov/pubmed/33227945
http://dx.doi.org/10.3390/biom10111570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699199/
https://www.ncbi.nlm.nih.gov/pubmed/33227945
http://dx.doi.org/10.3390/biom10111570

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