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Comprehensive Genomic Profile of Heterogeneous Long Follow-Up Triple-Negative Breast Cancer and Its Clinical Characteristics Shows DNA Repair Deficiency Has Better Prognostic

Triple-negative breast cancer (TNBC) presents a marked diversity at the molecular level, which promotes a clinical heterogeneity that further complicates treatment. We performed a detailed whole exome sequencing profile of 29 Mexican patients with long follow-up TNBC to identify genomic alterations...

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Detalles Bibliográficos
Autores principales: Rojas-Jiménez, Ernesto, Mejía-Gómez, Javier César, Díaz-Velásquez, Clara, Quezada-Urban, Rosalía, Martínez Gregorio, Héctor, Vallejo-Lecuona, Fernando, de la Cruz-Montoya, Aldo, Porras Reyes, Fany Iris, Pérez-Sánchez, Víctor Manuel, Maldonado-Martínez, Héctor Aquiles, Robles-Estrada, Maybelline, Bargalló-Rocha, Enrique, Cabrera-Galeana, Paula, Ramos-Ramírez, Maritza, Chirino, Yolanda Irasema, Alonso Herrera, Luis, Terrazas, Luis Ignacio, Oliver, Javier, Frecha, Cecilia, Perdomo, Sandra, Vaca-Paniagua, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699204/
https://www.ncbi.nlm.nih.gov/pubmed/33227964
http://dx.doi.org/10.3390/genes11111367