Genetic Variants of the NKG2C/HLA-E Receptor–Ligand Axis Are Determinants of Progression-Free Survival and Therapy Outcome in Aggressive B-Cell Lymphoma

SIMPLE SUMMARY: NKG2C and its ligand HLA-E represent key molecules for NK cell-mediated immune responsiveness. However, the impact of genetic variants in NKG2C and HLA-E on clinical outcomes of aggressive B-cell non-Hodgkin lymphoma patients (B-NHL) has not been clarified. In this study, we analyzed...

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Detalles Bibliográficos
Autores principales: Wagner, Bettina, Dührsen, Ulrich, Hüttmann, Andreas, Nückel, Holger, Michita, Rafael Tomoya, Rohn, Hana, Schramm, Sabine, Horn, Peter A., Rebmann, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699209/
https://www.ncbi.nlm.nih.gov/pubmed/33218185
http://dx.doi.org/10.3390/cancers12113429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699209/
https://www.ncbi.nlm.nih.gov/pubmed/33218185
http://dx.doi.org/10.3390/cancers12113429

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