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Keeping α-Synuclein at Bay: A More Active Role of Molecular Chaperones in Preventing Mitochondrial Interactions and Transition to Pathological States?

The property of molecular chaperones to dissolve protein aggregates of Parkinson-related α-synuclein has been known for some time. Recent findings point to an even more active role of molecular chaperones preventing the transformation of α-synuclein into pathological states subsequently leading to t...

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Detalles Bibliográficos
Autores principales: Aspholm, Emelie E., Matečko-Burmann, Irena, Burmann, Björn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699229/
https://www.ncbi.nlm.nih.gov/pubmed/33227899
http://dx.doi.org/10.3390/life10110289