Concentration- and pH-Dependent Oligomerization of the Thrombin-Derived C-Terminal Peptide TCP-25

Peptide oligomerization dynamics affects peptide structure, activity, and pharmacodynamic properties. The thrombin C-terminal peptide, TCP-25 (GKYGFYTHVFRLKKWIQKVIDQFGE), is currently in preclinical development for improved wound healing and infection prevention. It exhibits turbidity when formulate...

Descripción completa

Detalles Bibliográficos
Autores principales: Petruk, Ganna, Petrlova, Jitka, Samsudin, Firdaus, Giudice, Rita Del, Bond, Peter J., Schmidtchen, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699335/
https://www.ncbi.nlm.nih.gov/pubmed/33228042
http://dx.doi.org/10.3390/biom10111572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699335/
https://www.ncbi.nlm.nih.gov/pubmed/33228042
http://dx.doi.org/10.3390/biom10111572

Ejemplares similares